Gastric and EGJCancer
EUNE
European Union Network of Excellence
General Coordinators: William Allum (UK) – Hans Joachim Meyer (Ger)
Topic Team Leaders
Traslational Research R. Seruca (Port) D. Roukos (Greece)
Standards and Audit G. De Manzoni (It) C. Wittekind (Ger)
Early Diagnosis H. Barr (UK) J. Haringsma (Neth)
Development of Surgical Treat. M.De Giuli (It) A. Sendler (Ger)
Adequate Surgery for EGJ Tum. T. Lerut I. Kulig (Poland)
Adjuvant and Neoadjuvant T H.Hartgrink (Neth) C. Schuhmacher (Ger)
Prevention of Peritoneal Rec. F. Gilly (Fr) A. Garofalo (It)
Education and Training K. Park (UK) W. Nowak (Poland)
Main Targets:
1)Traslational Research
- Organization of BIODATABANK
- Cross over study through all the Clinical trials
- Main targets:
- Individuating predictive prognostic factors
- Individuating molecular parameters in relation to chemotherapy response
- Establish the prognostic value of isolated cancer cells in the bone marrow
- Staging System
- - To adopt the TNM System
- Validation of D2 lymphoadenectomy
- - As adequate surgery, following the parameters of the TNM system
3)Developments in Surgical Treatment
- consensus statement on:
Lymphoadenectomy following the rules of the D2 dissection with a retrieval of at least 25 lymphonodes has to be considered
ADEQUATE SURGERY
- Splenectomy: waiting for the results from JCOG Trial
- European Registry on particular topics
- Minimal Invasive Surgery
- Sentinel Node Mapping
- Jejunal Pouch Reconstruction
- Incidence on the quality of life
4)EGJ Tumors
- Approval and adoption of Siewert’s Classification
- Surgical Approach
- Adequate Surgery
5) Development of new Mutimodal Therapies
- Adjuvant Chemo
- Neoadjuvant Chemo
- Radio – Chemotherapy
- HIPEC (Hypertermic Intraperitoneal Chemotherapy)
- Are they useful?
- In which cases?
- Why? (Biological characterization)
6) in search of definition
- EGC
- Educational Programs